Psychiatry

Lege Artis Medicinae

APRIL 30, 2024

[The misuse of insulin ]

BUZÁS György Miklós

[Discovered in 1922, insulin has saved millions of lives, and improved the quality of life of diabetic patients: it was and is the mainstay of antidiabetic treatment. Like many discoveries, however, it can also be used incorrectly, causing harm and even death. Attempted or terminated suicide as an important example of insulin misuse must be distinguished from accidental, deliberate or factitious insulin overdoses. With increasing prevalence of diabetes and spreading use of pharmaceutical insulin products, such cases are expected to rise. Regular, human and analogue insulins are used for this purpose. Famous killings by insulin were reported in both scientific and lay literature as reality cases, and achieved high rates of publicity. Insulin shock therapy used in psychiatry and post-vagotomy insulin tests can also have side effects or end up lethally. Insulin and insulin-like growth factor are also applied as drugs for doping. Investigations to prove insulin misuse benefit from the most advanced methods of clinical chemistry. ]

HUN 2024;34(4)

Lege Artis Medicinae

APRIL 30, 2024

[Medical and the life history models in clinical psychology ]

PLÉH Csaba

[This study presents the dual nature of the classical medical and the more flexible life history model of mental disorders in the last almost two hundred years of psychological way of thinking. One way of basic interpretations considers the mental disorders as an outcome of any kind of disturbed biological functions. Within this classification, some considerations – according to Rokitansky’s pathological doctrine – couple the mental disorders to the disorders of specific anatomical brain structures. The other way of interpretation complies with Claude Bernard’s ideas, thus mental disorders are of regulatory origin. In our days there were emerging strong evolutionary and neurobiological understandings in the biological mental pathology and the key issue is their interrelation. The other way of traditional interpreting mental disorders starts from life history and the constant interpretive work of humans. Our symptoms are based on special meaning and valance having attributed to life events. As a mainstream in this regard, this study presents the works of Sigmund Freud and Karl Jaspers. The conclusion is that biological ad life history interpretations must cooperate for understanding of mental disorders. ]

HUN 2024;34(4)

Lege Artis Medicinae

APRIL 30, 2024

[Female aspects of dementia ]

KOVÁCS Tibor

[Dementia is a new epidemic of the 21st century in all aging societies. Besides old age, female sex is one of the non-modifiable risk factors of dementia. Alzheimer’s disease is responsible for two thirds of all dementia cases, two thirds of which are female patients. This female excess is not seen in other degenerative (such as Lewy body or frontotemporal dementia) conditions or vascular dementias. In the background of this additional risk there are primarily hormonal differences suspected. The later developing menopause decreases the risk of dementia. Albeit, the beneficial role of oestrogen seemed to be verified by animal tests and human data, the hormone replacement therapy has not justified the expectations: its outcomes were clearly without benefits in preventing dementia, thus its administration is not recommended in the clinical practice. These contradictory outcomes may be explained by the time window of hormone replacement therapy, which should be explored by further research programs. This study summarises all aspects of female dementia by narrative review of the concerning literature. ]

HUN 2024;34(4)

Clinical Neuroscience

MARCH 30, 2024

Personalized analysis of pain–weather associations: a pilot study

TUBOLY Gábor , HORVÁTH Gyöngyi , NAGY Kamilla , NAGY Edit

It is a wellknown belief that weather can influence human health, including pain sensation. However, the current data are controversial, which might be due to the wide range of interindividual differences. The present study aimed to characterize the individual pain–weather associations during chronic pain by utilizing several data analytical methods.

ENG 2024;77(3-4)

Clinical Neuroscience

MARCH 30, 2024

Neuropathic pain and mood disorders in earthquake survivors with peripheral nerve injuries

HALIL Can ALAYDIN, GUL Melisa BOZDOGAN, RUMEYSA PALTACI, ZULFIKAR ARLIER, HALIT FIDANCI, MEHMET YILDIZ

Natural disasters, such as earthquakes, frequently result in mood disorders among affected individuals. It is established that neuropathic pain arising from traumatic neuropathies is also linked to mood disorders. This study investigates the influence of neuropathic pain on the development of mood disorders in earthquake survivors with peripheral nerve injuries, following the earthquake centered in Kahramanmaraş on February 6, 2023.

ENG 2024;77(3-4)

Clinical Neuroscience

MARCH 30, 2024

Validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale

CELIK Buket , BILIK Ozlem, KOÇBILEK Deveci Zeynep , DAMAR Turhan Hale , ÖZ Didem , DENIZMEN Zeynep

Delirium is a common complication developing in el­derly patients. Therefore, it is important to diagnose delirium earlier. Family caregivers play an active role in early diagnosis of de­lirium and build a bridge between health professionals and patients. The purpose of this research was to achieve the validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale (I­AGeD).

ENG 2024;77(3-4)